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Showing posts from January, 2021

Dipyridamole,a game changer to stop the spread of Corona Virus needs Consideration

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  Dipyridamole,a game changer to stop the spread of Corona Virus needs Consideration   Nowadays, the spread of Corona Virus is the main threat to human kind all over the world. Undoubtedly, it's required for every body to stop the spread of Corona Virus. In order to stop the spread of Corona Virus, we need to dive a little in the process of Corona Virus Replication and transcription.  DNA transcription   It is a process in which Covid 19 RNA is copied into another one by the enzyme RNA Polymerase adding nucleotide to the 3' end of the strand. Transcription process involves three steps, initiation, elongation and termination. Initiation RNA Polymerase binds to the template RNA strand at the promoter region, TATA box, separating and providing the base to make a chain. Elongation RNA Polymerase reads the template to make chains from 3' to 5' direction to form mRNA. Termination When RNA Polymerase moves along the template forming mRNA until it reaches the terminat

Dipyridamole, the potential drug to be considered in stopping RNA Replication of Covid 19

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   Dipyridamole, the potential drug to be considered in stopping RNA Replication of Covid 19   Dipyridamole(Persantin), must be used only under the Prescription of Physician.   Dipyridamole                        Dipyridamole is used for anti coagulation, anti viral and and anti inflammatory actions. As Covid 19 has inflammation and coagulation effects by Cytokines Storm, the possible action of Dipyridamole can be considered as a therapeutic way in treating severely ill Covid 19 patients suffering from blood clotting.                             Diyridamole has a Phoshodiesterase enzymes that can break down the RNA replication of Covid 19. This Phoshodiesterase can break down DNA and RNA of Covid 19.                             Dipyridamole acting as a Phoshodiesterase inhibitor provide the effects of Adenosine blocking nucleosides binding to Covid 19 RNA.                                  Phoshodiesterase inhibitor(dipyridamole)           It is a drug used for blocking of Phoshodiestr